Recurrent Painful Perianal Subcutaneous Angiomatoid Fibrous Histiocytoma
نویسندگان
چکیده
Angiomatoid fibrous histiocytoma (AFH) is a rare, lowgrade malignant soft-tissue tumor most commonly occurring in the extremities of children and young adults and has a low potential of local recurrence and metastasis. Here, we present a case of recurrent subcutaneous perianal AFH. After an initial diagnosis as a sebaceous cyst, we were able to use immunohistochemical findings to correctly identify the mass as an AFH. The patient was effectively treated after 3 surgical resections. This case emphasizes the need to correctly diagnose softtissue tumors using a variety of diagnostic modalities to ensure that the patient receives proper treatment. (Medicine 93(28):e202) Abbreviations: AFH = angiomatoid fibrous histiocytoma, CT = computed tomography, FISH = fluorescence in situ hybridization, MRI = magnetic resonance imaging, RT-PCR = reverse transcription polymerase chain reaction, T1WI = T1-weighted image, T2WI = T2-weighted image, WHO = World Health
منابع مشابه
Retroperitoneal angiomatoid fibrous histiocytoma: A case report and review of the literature
Angiomatoid fibrous histiocytoma (AFH) is a rare, low-grade malignant potential soft tissue tumor which occurs most commonly in children and young adults. Only a few case reports have been described that typically occur in the extremities of the deep dermis and subcutaneous tissue, followed by the trunk, as well as the head and neck. A case report of retroperitoneal AFH is described. This prese...
متن کاملSubcutaneous Angiomatoid Fibrous Histiocytoma Mimicking Metastatic Melanoma
Angiomatoid fibrous histiocytoma is an uncommon soft-tissue tumor of intermediate malignancy that is often misdiagnosed initially. As there is not one immunohistochemical marker that consequently stains positive or negative for angiomatoid fibrous histiocytoma, molecular diagnostics are becoming more widely used. So far three translocations have been reported to arise in angiomatoid fibrous his...
متن کاملAneurysmal ("angiomatoid") fibrous histiocytoma in a child.
A case of aneurysmal ("angiomatoid") fibrous histiocytoma (AFH) in a 12-year-old girl is presented with its unusual clinicopathologic features. The lesion had the full microscopic characteristics of AFH described in prior reports, but it also had some features that differed from the original description of the disorder, such as the involvement of subcutis, its occurrence in the scalp, and a doc...
متن کاملIntracranial angiomatoid fibrous histiocytoma presenting as recurrent multifocal intraparenchymal hemorrhage.
Angiomatoid fibrous histiocytoma (AFH) is a rare soft-tissue neoplasm that most commonly appears in the limbs, typically affecting children and young adults. The tumor has a propensity for local recurrence and recurrent hemorrhage but rarely for remote metastasis. To date, only 2 reports have documented an intracranial occurrence of the tumor (1 of which was believed to be metastatic disease). ...
متن کاملAngiomatoid fibrous histiocytoma: a series of seven cases including genetically confirmed aggressive cases and a literature review
BACKGROUND Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor of intermediate biologic potential. Because of its rarity and nonspecific radiological and diverse pathological findings, AFH is often clinically misdiagnosed. However, few clinical reports have described this tumor. As reported herein, we analyzed the clinical and radiological features and clinical outcomes of AFH. ...
متن کامل